49ers vs. Seahawks as it happened: Reaction, analysis of SF's 20-17 loss

What to Know

• Immediately after the Week 11 game ends, watch "49ers Postgame Live" on NBC Sports Bay Area or stream the show in the NBC Sports app for full reaction, analysis and interviews.
• The 49ers fall to 5-5 with a crushing 20-17 loss to the Seahawks. Geno Smith's 13-yard touchdown run with 12 seconds remaining in regulation gave Seattle the stunning win over San Francisco.
• The loss drops the 49ers a full game behind the NFC West-leading Arizona Cardinals (6-4). San Francisco, Seattle and the LA Rams now all have 5-5 records.
• Wide receiver Jauan Jennings was the star of the game for the 49ers, catching 10 passes for 91 yards and a touchdown.
• Running back Christian McCaffrey's second game of the season was better than his first. The 2023 NFL Offensive Player of the Year had 19 rushing attempts for 79 yards, while catching four passes for 27 yards.
• Quarterback Brock Purdy completed 22 of 29 passes for 162 yards and one touchdown with one interception. He also scrambled five times for 40 yards.
• Cornerback Isaac Yiadom had the 49ers' only interception of the game, recording his first pick with San Francisco early in the third quarter.
• Edge rusher Nick Bosa came into the game battling a hip injury but still managed to record 1.5 sacks in the win. The 2022 NFL Defensive Player of the Year later left the game due to his ailment and didn't return. Leonard Floyd combined with Bosa on a sack and picked up another late in the fourth quarter, while Yetur Gross-Matos also had a sack.