49ers

The 49ers are getting ready to open the playbook by offering rare memorabilit and one-of-a-kind experiences to help give something back for the holidays.

The San Francisco 49ers are looking to bounce back as they face the Buffalo Bills on Sunday Night Football. Raj Mathai speaks with NBC Sports Bay Area’s Jennifer Lee Chan on this weekend’s matchup.

Josh Jacobs rushed for 106 yards and matched a career high with three touchdowns and the Green Bay Packers trounced the short-handed San Francisco 49ers 38-10 on Sunday.

Geno Smith scored on a 13-yard scramble with 12 seconds remaining and the Seattle Seahawks snapped a six-game losing streak against the San Francisco 49ers with a 20-17 victory on Sunday.

Join NBC Bay Area and Telemundo 48 on Dec. 1 for a 49ers-Bills viewing party at Thrive City outside Chase Center in San Francisco.

The season debut of Christian McCaffrey helped make the San Francisco 49ers offense look more like it did a year ago than it did in an up-and-down first half of the season.

San Francisco 49ers coach Kyle Shanahan called a sideline spat involving star receiver Deebo Samuel and two teammates an “overreaction” and said the team has put it to rest.

When the 49ers needed it most, Brock Purdy made enough big plays in the fourth quarter to deliver San Francisco a rare fourth-quarter comeback with a 23-20 victory over the Bucs.

The Seattle Seahawks announced Monday they waived linebacker Tyrel Dodson, their leading tackler, ahead of facing the San Francisco 49ers in Week 11.

Taybor Pepper speaks to reporters following the San Francisco 49ers’ 23-20 win over the Tampa Bay Buccaneers on Sunday at Raymond James Stadium.

San Francisco quarterback Brock Purdy speaks with reporters after the 49ers’ win over the Tampa Bay Buccaneers on Sunday at Raymond James Stadium.

Jake Moody redeemed himself after missing three earlier field goals by booting a 44-yarder as time expired to give the San Francisco 49ers a 23-20 victory over the Tampa Bay Buccaneers in running back Christian McCaffrey’s season debut. In his first game back after being sidelined three weeks with a sprained ankle, Moody also kicked field goals of 28 and...

The San Francisco 49ers have been aggressive at the trade deadline under coach Kyle Shanahan and general manager John Lynch, often adding big-name players to fuel late-season runs.

San Francisco 49ers Nick Bosa and Golden State Warriors head coach Steve Kerr took time on Wednesday to respond to the presidential election results.

San Francisco 49ers All-Pro running back Christian McCaffrey returned to practice for the first time in nearly two months as he hopes to return from an Achilles tendon injury for the second half of the season. The Niners opened the practice window for McCaffrey, giving the team a three-week window to activate him from injured reserve. McCaffrey took part in...

After a somewhat shaky first half of the season for the defending NFC champion San Francisco 49ers, they are hoping to follow a similar pattern to the past two seasons.

San Francisco 49ers star Nick Bosa recently crashed a postgame interview and it has a lot of people talking.

San Francisco 49ers star Nick Bosa recently crashed a postgame interview and it has a lot of people talking.

Brock Purdy threw a touchdown pass and ran for another score to send the San Francisco 49ers into their bye week on a high note with a 30-24 victory over the Dallas Cowboys on Sunday night. Janelle Wang and Raj Mathai have details.